Testicular Regression

What is Testicular Regression?

Testicular regression is a condition in which the testicles are absent. It is different from undescended testicles. Other names for this condition include testicular regression syndrome, anorchia, and vanishing testes.

What Causes Testicular Regression? 

The exact cause of testicular regression is not well understood. Theories suggest genetic or hormonal causes, or early testicular torsion and atrophy occurring in the womb before birth.

How is Testicular Regression Diagnosed?

Diagnosis involves confirming the absence of testes. This is typically done through exploratory surgery. Additional diagnostic indicators include:

  • Chromosomal Analysis: Individuals with testicular regression typically have 46, XY chromosomes.
  • Hormone Testing: Low testosterone levels, elevated FSH (Follicle Stimulating Hormone) and LH (Luteinizing Hormone) levels, and low anti-Müllerian hormone levels are indicative of this condition.

How is Testicular Regression Treated? 

Treatment for testicular regression focuses on supporting physical and psychological well-being. Options include:

  • Psychological Support: Emotional and psychological support is crucial for individuals dealing with testicular regression.
  • Testosterone Supplementation: At puberty, testosterone supplementation is required for pubertal body changes and to maintain bone and metabolic health.
  • Testicular Prostheses: If desired, testicular prostheses can be used for cosmetic and psychological reasons.

Related Programs