Lurie Children’s (formerly Children’s Memorial Hospital) performed its first transplant in 1964 and has remained a leader in transplant surgery and advanced hepatobiliary (related to liver, gallbladder or bile ducts) surgery ever since. We are one of only eleven children’s hospitals nationwide to have performed more than 1,000 solid organ transplants.

Each year, the center performs 50 stem cell transplants and 50 solid organ transplants on average, which is the largest number of pediatric organ transplants at a single center in Illinois. Our highly experienced transplant surgeons also use innovative surgical techniques that spare patients the need for a transplant when possible.

The hospital’s Siragusa Transplantation Center ranks among the top pediatric transplant centers in the country, not just in volume, but in patient survival rates. E​ach of our transplant programs have high rates of graft (transplant) success and patient survival three years after surgery. 

Our Approach

We specialize in family-centered care, which means we provide emotional and social support to the whole family along with the patient.

Our care is also uniquely long-term. The center’s staff provides follow-up care into patients’ teenage years or young adulthood, checking their development to make sure they flourish. A joint program with Northwestern Memorial Hospital, a leader in adult transplantation, lets us offer lifelong follow-up care for transplant recipients. This partnership also lets eligible adult relatives donate certain organs and tissues to children as living donors.

Our transplant program pioneered the use of support services for children receiving a transplant and for their families. We address the medical, behavioral and emotional concerns of children and families through support programs, including:

Nationally-Ranked Care

Lurie Children’s continues to be the #1 children's hospital in Illinois and is ranked in 9 specialties by U.S. News & World Report.

Organ Transplant Programs

The center is home to five outstanding transplant surgery programs for children of all ages and for young adults with childhood diseases. These program​s include heart, kidney, liver, intestine and stem cell transplant. 

Our Pediatric Transplant Surgeons & Specialists

The Siragusa Transplantation Center uses a collaborative approach that brings together the best medical and surgical transplant care. A pediatric transplant surgeon, Riccardo Superina, MD, provides surgical direction for the center. He has pioneered procedures now used around the world. Estella Alonso, MD, is the medical director for the center.

All of our doctors and nurse practitioners have advanced training in pediatrics or adolescent medicine, allowing them to meet the unique needs of children and teens. Our entire staff is committed to giving your child the best possible care.


For more information, please call 1.800.543.7362 (1.800.KIDS DOC®). 

Traveling from out-of-state? Our Destination Services team is available to help make your experience at Lurie Children's go as smoothly as possible. Learn more.

Transplant Remote Consultations & Second Opinions

Whether you anticipate your child needing an organ transplant in the future, interested in multiple listing for organ transplant, or would like a second opinion on post-transplant care, the transplant remote consultation and second opinion program can help. 

Via telemedicine, our transplant providers are available for an initial consultation to review your care, explain our transplant process, and provide second opinions of post transplant care treatment plans before deciding if traveling to Lurie Children’s would be the right choice for you.

Learn More

Transplantation News & Stories

Sawyer’s Fighting Chance: His Own Father

Newborn baby Sawyer battled a life-threatening liver condition for months until the most perfect donor was found and turned everything around: his own dad.  

Read more

High-Risk Pediatric Heart Transplants with Drs. Michael Mongé and Philip Thrush

In this episode, Dr. Michael Mongé and Dr. Philip Thrush discuss how their team is uniquely equipped to take on high-risk pediatric heart transplantation patients, who are often turned away at other hospitals.

Read more

‘She Never Gave Up:’ Jasy’s Heart Health Scare Turns Remarkable Recovery

As a healthy 10-year-old, Adriana didn’t suspect anything serious when her daughter, Jasy, developed a persistent cough. Learning she was in heart failure and would eventually need a transplant began a journey paved with perseverance and persistence. 

Read more

Haytham Doing Better Than Ever Following Liver Transplant From Altruistic Donor

Two-year-old Haytham had already overcome many challenges in his young life and needed a liver transplant. One altruistic stranger was a match.

Read more

More than five years since their transplant, 'liver sisters' are thriving

Neither Ava’s mom, Michelle, nor Kendall say they will forget the day they heard a liver became available for both patients – from the same donor. 

Read more

‘Fighter’ Grace marks 10 years since her kidney transplant

Grace was only 19 months old when she had a kidney transplant at Lurie Children’s. Ten years later, the scars are virtually the only evidence of her health challenges. 

Read more


The Siragusa Transplantation Center is a national leader in pediatric transplant research. Our physician-researchers have pioneered influential new methods of studying pediatric diseases and transplantation. Through many clinical and laboratory studies, we are committed to research directly related to improving your child’s health.


Your support is vital in helping us fund patient-focused support services and programs. Your gifts to the center also help us train tomorrow’s specialists and conduct vital research to track and improve outcomes.

To learn more, please e-mail the Ann & Robert H. Lurie Children’s Hospital of Chicago Foundation at or call 312.227.7500.