Anatomic Pathology

The Anatomic Pathology Division offers state-of-the-art diagnostic services in Surgical Pathology, Cytopathology, Hematopathology and Autopsy Pathology.  These four main areas are supported by a variety of laboratories including Histology, Hematology, Flow Cytometry, Microbiology, Molecular Genetics and Cytogenetics. Pathological material from outside institutions is reviewed upon request.

Surgical Pathology

Surgical Pathology is a comprehensive diagnostic service that processes over 7,000 specimens every year. Our board-certified pathologists are experts in most subspecialty areas and offer complete services in pediatric surgical pathology. Areas of intense subspecialty expertise include the fields of neuropathology, renal tumors (including Wilms tumor), germ cell tumors, gastroenterology and hepatic pathology, hematopathology, neuropathology, cardiac pathology, lung pathology, soft tissue tumors, genitourinary pathology and medical renal pathology, among others. Special Procedures employed include immunohistochemistry, immunofluorescence, in situ hybridization, and molecular diagnosis by RT-PCR and FISH.


The Cytopathology service processes an average of 500 cytology preparations every year, corresponding mostly to bronchial alveolar lavages and body fluid cytology (CSF, pleural, peritoneal, pericardial fluids). Approximately 100 fine needle aspirations are performed annually which include thyroid, bone and soft tissue lesions, among others.


The hematopathology service interprets approximately 400 bone marrows, and 100 lymph node and tissue biopsies each year. We use a multidisciplinary approach that integrates the morphology, immunohistochemistry, flow cytometry immunophenotyping, traditional cytogenetics, and FISH, as well as molecular diagnostics.  The common disease entities for which we have expertise include acute lymphoblastic Leukemia/lymphomas, acute myeloid leukemia/myeloid sarcomas, chronic myeloid leukemia, Burkitt lymphoma, Hodgkin lymphomas, NK and T cell neoplasms, histiocytic and dendritic cell neoplasms, congenital bone marrow failure syndromes, post-transplant lymphoproliferative disorders, and other neoplastic and non-neoplastic hematopoietic lesions.

Autopsy Pathology

The division of Anatomic Pathology performs post-mortem examinations by request of Lurie Children’s physicians on an average of 30 patients each year.

The Division of Anatomic Pathology supports the research and academic missions of the institution through participation in clinical research and in the education of fellows, residents, medical students, and medical technology students.

Division Head: Pauline Chou, MD

Senior Practice Manager:  Gwendolyn Robles, MLS(ASCP)CM, MBA

Department of Pathology and Laboratory Medicine
225 E. Chicago Ave., Box 17
Chicago, IL 60611-2605
Telephone: 312.227.3973
Facsimile: 312.227.9616

Histology Manager:  Lisa Van Valkenberg, HT(ASCP)
Telephone: 312.227.3972