Food Allergy Research

Clinical Research Studies

Lurie Children’s Division of Allergy and Immunology is at the cutting edge of food allergy clinical research. We offer our patients with food allergy the newest treatments as well as opportunities to be part of studies in hopes to discover more treatments and a cure. 

We are currently recruiting patients in numerous food allergy studies. Learn more about our current trials:

Zileuton for Food Allergy

Principal Investigator: Abigail Lang, MD MSCI
Brief Description of Study:
We are conducting a study to find out if a currently FDA-approved medicine for asthma called zileuton might be able to stop food allergens from being absorbed and may have the potential to stop anaphylaxis to foods.
Key Inclusion/Exclusion Criteria:
Enrolling patients ages 12-17 with a food allergy EXCEPT for peanut allergy
Contact:
AllergyStudy@luriechildrens.org or 312.227.6474


A 52-week multicenter, randomized, double-blind, placebo-controlled study to assess efficacy and safety of remibrutinib (LOU064) in adult and adolescent participants with IgE-mediated food allergy

Primary Investigator: Abigail Lang, MD MSCI
Brief Description of Study: The purpose of this study is to evaluate if a medicine called remibrutinib taking twice a day can work to protect people with food allergies to peanut, cow’s milk (cooked and uncooked) or hen’s egg (cooked and uncooked). This is a randomized clinical trial that will compare the active study medicine to placebo to see if the medicine works and is sagfe.
Key Inclusion/Exclusion Criteria: Participants need to be 12 to 26 years of age and have positive allergy testing and history of reaction to peanut, milk, or egg;
Lurie Children’s will soon be screening participants, if interested please see contact information below.
Contact: AllergyStudy@luriechildrens.org or 312.227.6474


Determination of Hypoallergenicity of an Extensively Hydrolyzed Infant Formula in Infants and Children with Cow’s Milk Allergy (AL60)

Primary Investigator: Elizabeth Lippner, MD, MA
Brief Description of Study: The purpose of this study is to see if a specially broken-down milk protein formula is safe for babies and children with a confirmed cow’s milk allergy. The formula is designed to lower the chance of  an allergic reaction.
Key Inclusion/Exclusion Criteria: Enrolling patients ages 6 months-12 years with an IgE mediated cow’s milk allergy. 
Contact: AllergyStudy@luriechildrens.org or 312.227.6474

Basic Science and Public Health Research

The Center for Food Allergy and Asthma Research (CFAAR), part of the Institute for Public Health and Medicine (IPHAM) at Northwestern University Feinberg School of Medicine and Ann Robert H. Lurie Children’s Hospital of Chicago, aims to find answers and shape policies surrounding food allergy, asthma and other allergic conditions.

Led by Ruchi Gupta, MD, MPH, CFAAR is comprised of three interdisciplinary and collaborative research cores: 1.) Public Health Data Repository Core, 2.) Clinical Research Core and 3.) Community/School Outreach Core. These cores are led by experts in the fields of epidemiology, health services research, health behavior, patient care, and advocacy seeking to make meaningful improvements in the health of children, adults, and families living with allergic disease.