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Specialties & ConditionsEpilepsy Program Research - Clinical Trials
Here at Lurie Children’s, our research team works tirelessly to bring our patients and families an abundance of clinical research opportunities, in a mission to discover new cures, every day. Our multidisciplinary team of physician-scientists conduct various research projects to help promote patient care and better educate families. We participate in studies funded by the National Institute of Health (NIH), pharmaceutical companies and our own investigator-initiated studies. We hope our research efforts will improve treatment for children with epilepsy.
Our current focus is in precision medicine, which strives to determine optimal personalized treatment methods based on genetic testing results. We hope to achieve the same success as with our existing studies, which will help our patients tremendously.
Learn more about Epilepsy Precision Medicine - Research Studies
An Open-Label Study to Investigate the Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Antisense Oligonucleotide STK-001 in Children and Adolescents with Dravet Syndrome
An Open-Label Extension Study for Patients with Dravet Syndrome who Previously Participated in Studies of STK-001
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Patients With Developmental and/or Epileptic Encephalopathies
A Phase 2, Prospective, Interventional, Open-Label, Multi-Site, Extension Study to Assess the Long-Term Safety and Tolerability of TAK-935 (OV935) as Adjunctive Therapy in Patients with Developmental Epileptic Encephalopathies Including Dravet Syndrome, Lennox Gastaut Syndrome, CDKL5 Deficiency Disorder, and Chromosome 15 Duplication Syndrome (ENDYMION)
A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome
Natural History Study of Infants and Children with SCN1A-positive (SCN1A+) Dravet (ENVISION)
A Phase 3 Study of Adjunctive XEN496 in Pediatric Subjects with KCNQ2 Developmental and Epileptic Encephalopathy
An Open-label, Randomized Trial to Assess the Safety, Pharmacokinetics, and Exploratory Efficacy of Adjunctive Cannabidiol Oral Solution (GWP42003-P) Compared with Standard of Care Antiepileptic Therapy, in Patients Age 1 Month to Less Than 12 Months of Age with Tuberous Sclerosis Complex Who Experience Inadequately-controlled Seizures
Copper Histidinate Treatment for Menkes Disease
Ketogenic Diet with D,L-Beta-Hydroxybutyrate Medical Food Formulation for Pediatric Patients with Drug Resistant Epilepsy (KEEPER)
