L. Nelson Sanchez-Pinto, MD, MBI, Principal Investigator
Dr. Sanchez-Pinto is a pediatric critical care physician and biomedical informatics specialist. His research focuses on the intersection of these two disciplines and the application of data science principles to critical care problems. A recipient of a Master’s degree in Biomedical Informatics, he is interested in the discovery and evaluation of data-driven phenotypes (or subgroups) of critical illness. He is the principal investigator of PRIMER PICU, a study that aims to integrate clinical information, physiologic trends, and multi-omics data (that is, information from the genome, microbiome, and epigenome), to discover these novel phenotypes. The discovery of these phenotypes will hopefully lead to the development of more effective targeted therapies for critically ill children.
Bria M. Coates, MD, Co-Investigator
Dr. Coates is a physician-scientist who specializes in the intersection between pediatric critical care medicine and inflammatory responses to illness. Her research explores differences in the inflammatory response to viral respiratory infections in children and adults with the goal of understanding why young children and elderly adults bear a disproportionate burden of morbidity and mortality associated with viral respiratory infections. Her lab is currently investigating the role of innate immune responses in influenza infections. These results may contribute to the broader understanding of innate immunity and its role in critical illness.
Thomas P. Shanley, MD, Co-Investigator
Dr. Shanley is Chair of the Department of Pediatrics at Ann & Robert H. Lurie Children’s Hospital of Chicago and Founders’ Board Centennial Professor and Chairman of the Department of Pediatrics at Northwestern University Feinberg School of Medicine. He also serves as President and Chief Research Officer of the Stanley Manne Children’s Research Institute. As a research leader, his focus is to improve understanding of the molecular basis of inflammatory diseases that afflict critically ill young patients. Over the course of his career, he has conducted basic, translational and clinical research and has a keen interest in making the translational spectrum more efficient so that benefits reach patients faster.
Patrick C. Seed, MD, PhD, Co-Investigator
Dr. Seed is a clinician-scientist with board certification and active practice in Pediatrics and Infectious Diseases. He also holds a doctoral degree in Microbiology and Immunology. At Northwestern and Lurie Children’s Hospital, Dr. Seed is the Division Head for Pediatric Infectious Diseases and the Associate Chief Research Officer for Basic Science at the Stanley Manne Children’s Research Institute. His research lab studies the molecular pathogenesis of genitourinary tract host-pathogen interactions, the assembly of the microbiome and its clinical ramifications, and anti-infective drug-discovery.
Department of Pathology and Laboratory Medicine (DPLM) at the Ann & Robert H. Lurie Children's Hospital of Chicago, Biospecimen Processing and Storage
Shannon Haymond, PhD
Robert Falkiner, MBA, MT(ASCP)
James Bellis, MS, PACM
The research laboratory at Ann & Robert H. Lurie Children's Hospital of Chicago is CLIA certified and housed within the clinical laboratory facilities located on the 8th floor. The clinical laboratory director is also responsible for oversight of laboratory research services with daily operations managed by the relevant clinical area manager. All research laboratory staff are highly trained and IATA certified. The lab currently provides support to over 120 investigator and sponsor initiated studies.