Because a patient needs to take increasing doses of Palforzia over time, there is a chance for anaphylaxis at each up-dosing. There are also risk factors like exercise, increases body temperature, illness and changes in hormones that may affect your child’s response to the daily dose of Palforzia making anaphylaxis possible. If your child has significant anxiety regarding anaphylaxis or the use of injectable epinephrine, Palforzia may not be right for your child.