Estrogen may increase the risk for conditions such as heart disease, diabetes, high cholesterol or blood pressure. These risks are greater in smokers, people who are obese and in people with a family history of these conditions.
Estrogen may cause blood clots, but this is relatively rare. Transdermal patches are recommended for people with high blood pressure or for cigarette smokers.
Estrogen may cause increased appetite, nausea, mood changes or headaches. There are also some uncommon side effects your provider will discuss with you.