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⚠ COVID-19 INFORMATION: Vaccine Information, Other Resources 

NASCAR Chicago Street Race (July 1 & 2)

Due to the NASCAR Chicago Street Race and adjacent activities, there will be rolling street closures and traffic congestion from 6/10 through 7/10. Please check nascarchicago.com before your appointment for the latest street closures and traffic and commuter information. For the most up-to-date CTA and Metra schedules, visit TransitChicago.com and Metra.com.

Lurie Children’s Home Specialties & ConditionsCystic Fibrosis ProgramOngoing Care & Health Maintenance Common Cystic Fibrosis Medications

Common Cystic Fibrosis Medications

The following medications are some of the most commonly used in the care of cystic fibrosis.

Digestive Tract Medications

Enzymes: Pancreatic enzymes are lacking in most children with CF, so these are taken to help digest protein and fat from food. The amount prescribed is based on a child’s weight and the dose will be adjusted often as a child grows.  Brand name enzymes include:

  • Creon®
  • Pancreaze®
  • Zenpep®

Each brand enzyme comes in multiple strengths. Generic enzymes should NOT be used for children with CF.

Vitamins

Certain vitamins are poorly absorbed in children with CF, and extra vitamins are needed to keep children healthy. They include:

  • AquADEK® - A multi-vitamin with extra vitamin A, D, E and K
  • Vitamax ® - A multi-vitamin with extra vitamin A, D, E and K
  • Complete Formulation (MVW) - A multivitamin with extra vitamin A, D, E and K
  • Vitamin D - Ergocalciferol (Vitamin D2)  or cholecalciferol (Vitamin D3)
  • Vitamin K - Phytonadione (Mephyton®)

Reflux Medications

These medications are needed to treat stomach reflux when it occurs. They are also prescribed to some children to help enzymes work better.

  • Ranitidine (Zantac®)
  • Proton pump inhibitor (Prevacid®, Prilosec® and others)

Laxatives

  • Enulose (Lactulose®) - A liquid syrup medicine given to young infants with constipation
  • Polyethylene glycol (MiraLax®) - A powder mixed in liquid for older infants with constipation
  • Ursodiol (Actigall®) - A medication prescribed to treat liver disease in CF

Inhaled or Nebulized Medications

  • Pulmozyme® - A preventive medication that helps break down mucous in the lungs making it easier to cough out
  • Bronchodilators (albuterol, Xopenex®) - These help open the airways to improve clearance of mucous
  • Hypertonic saline - A strong salt solution that helps restore a normal environment in the lungs and encourages a healthy cough
  • TOBI® - An antibiotic (tobramycin) that keeps certain bacteria (pseudomonas) from growing in the lungs

Steroids

These medications can lessen the inflammation or swelling in the airways. Although steroids are used less frequently, they may be prescribed for children who are having asthma-type symptoms in addition to CF. They can be given for a short time by mouth, or can be taken long-term in an inhaled or nebulized form.

Oral Antibiotics for Respiratory Illnesses

These are medications used to treat bacteria in the lungs or sinuses that can cause an infection. Common antibiotics used in CF include:

  • Amoxicillin and clavulanic acid (Augmentin®)
  • Cefdinir (Omnicef®)
  • Sulfamethaxazole and trimethoprim (Bactrim®), sometimes in combination with rifampicin (Rifampin®)
  • Ciprofloxacin (Cipro®)

Antibiotics are chosen based on what bacteria are found on respiratory cultures, the symptoms during an illness, any allergies and a child’s previous response to antibiotics.