What Causes Cavernomas?
Sometimes cavernomas are hereditary; this form of the condition is often associated with multiple cavernomas. Although this kind can happen in any family, it occurs at a higher rate among Mexican-American families because of a specific genetic mutation that has been found in this group. Each child of someone with the familial form has a 50% chance of inheriting the problem.
Up to 40% of solitary cavernomas may develop in the vicinity of another blood vessel abnormality called a venous angioma. Venous angiomas, also known as venous malformations or deep venous developmental anomalies (DVAs), usually don’t create problems unless they are close to cavernomas and consequently make it difficult to surgically remove the nearby cavernoma. Cavernomas are not visible on an angiogram because blood flows through the lesion slowly. This is one quality that makes cavernous angiomas different from arteriovenous malformations in which the blood flow is strong and fast and so are readily visible in an angiogram.