IRB Post-Approval Monitoring

In 2012, the Office of Research Integrity and Compliance (ORIC) launched the Post-Approval Monitoring (PAM) program to ensure that all research with human participants conducted at Lurie Children’s upholds the highest level of protections and is compliant with all applicable laws, rules, and regulations.

The PAM program also aims to:

  • Identify potential areas that need improvement, correction or targeted education.
  • Provide hands-on, one-on-one review and monitoring of the implementation of research; and
  • Create an open dialogue to promote education and sharing of best practices throughout the research program at Lurie Children’s.

The PAM program is an added mechanism in which the Institutional Review Board (IRB) fulfills the regulatory requirements to conduct periodic reviews, observe ongoing research and the consent process, as well as inspect research records.

All research studies involving human participants at Lurie Children’s qualify for PAM review and research study records are evaluated on a regular basis by ORIC staff. For more information on the PAM process, please see the additional resources listed below.

  • Overview of the PAM Program​: This document explains what to expect during a PAM review. 
  • PAM Program Checklists: The PAM review team utilizes two checklists during the review of study records. 

For questions regarding the PAM Program: 

  • Carol Macpherson, Clinical Research Quality Assurance & Improvement Specialist, ORIC, Ph: 312.503.7028