Center for Clinical Immunology

The Center for Clinical Immunology provides a venue for communication and education in the field of clinical immunology and fosters interdisciplinary collaboration with a focus on the immunopathology of disease states in children and adults.

This will be accomplished by developing clinical research activities that cross established disciplines, and by creating scientific forums that encourage these collaborative activities among the faculty at Northwestern University Feinberg School of Medicine, Lurie Children's, Manne Research Institute, Rush Medical College, University of Chicago, Loyola University Chicago, University of Illinois and other participants.


  • To investigate the development, structure and function of the immune system and the interactions of its components in health and disease.
  • To define the differences in the pathophysiology of selected illness in children versus adults.
  • To characterize the pathophysiology of pediatric primary and secondary immunodeficiency, infectious, allergic and autoimmune diseases in order to devise new trial interventions and to develop improved monitoring modalities.
  • To document the role of the mucosal immune system in pathogenesis of autoimmune diseases such as inflammatory bowel disease and food allergy.
  • To investigate the genetic basis of complex autoimmune diseases in order to increase our understanding of disease etiology, with the potential of improving treatment and developing preventive strategies.
  • To create multifaceted work groups to address common research goals.
  • To provide education concerning response to immunomodulatory therapeutic agents.


Lauren M. Pachman, MD
Dong Xu, MD, MS

Internal Advisory Board

  • Lauren Pachman, MD, Director; Professor, Pediatrics; Attending physician, Rheumatology
  • Aaruni Khanolkar, MBBS, PhD; Co-Director; Assistant Professor, Pathology
  • Alan Landay, PhD; Professor, Immunology-Microbiology, Rush University; The Thomas J. Coogan, Sr., MD, Professor
  • William J. Muller, MD, PhD; Assistant Professor, Pediatrics-Infectious Diseases
  • Richard M. Pope, MD; Chief and Professor, Division of Medicine-Rheumatology;  Mabel Greene Myers Professor of Medicine-Rheumatology
  • Robert P. Schleimer, PhD; Chief, Division of Medicine-Allergy-Immunology; Professor, Medicine-Allergy-Immunology and Otolaryngology - Head and Neck Surgery; Dr. Roy Patterson Professor of Medicine

Contact Information

Phone: 773.755.6375