Research Areas

The investigators, staff and trainees of Stanley Manne Children’s Research Institute contribute to laboratory, clinical, and health services and policy research. A primary goal of the research institute is to facilitate research leading to the most advanced pediatric health care.

Laboratory Research

At the Manne Research Institute, our scientists conduct bench research in laboratories using a variety of model systems and techniques. This type of research seeks to answer fundamental questions about health and disease, including medical conditions, human development and genetics, so that the results will lead to better therapies, devices or cures for patients. Find out more about our laboratory research.

Clinical Research

Biomedical research is conducted throughout Lurie Children’s departments and divisions. The collaborative spirit that our academic environment supports helps to make research progress and biomedical breakthroughs possible.

Clinical research is conducted using observational and Institutional Review Board-approved studies that seek to find the best medicines, devices and other therapies for specific conditions. These studies may be conducted only at Lurie Children’s, or at multiple institutions that collaborate, share results and publish their findings. Studies of therapeutic interventions are available on, the largest and most comprehensive list of clinical studies being conducted in the U.S. Find out more about our clinical research.

Community, Population Health and Outcomes

The Community, Population Health, and Outcomes pillar of the Stanley Manne Children's Research Institute is comprised individual investigators and research groups within the Mary Ann & J. Milburn Smith Child Health Outcomes, Research, and Evaluation Center. The Smith Child Health Center advances innovative research to improve the well-being, health, and healthcare of diverse populations of children. Find out more about our research.

Translational Research

By working together, and by combining the resources, techniques and expertise that Lurie Children's has to offer, our research goal is to enhance diagnosis, treatment and prevention of childhood diseases, as well as to improve outcomes.