Thalassemias

Martin, A.; Thompson, A. A.

Pediatr Clin North Am. 2013 Nov 19; 60(6):1383-91

Abstract

The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the alpha- or beta-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation. This article reviews current diagnostic approaches, complications, and disease management of thalassemia.

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