Successful prolonged use of recombinant human insulin-like growth factor-1 in a child with cystic fibrosis

Haupt, M. E.; Kim, E. E.; Prestridge, A. L.

Pediatr Pulmonol. 2011 May 28; 46(11):1137-41

Abstract

Growth failure is a common and complicated process in children with cystic fibrosis (CF). Growth hormone, which is becoming a more commonly used agent in such patients, has demonstrated beneficial effects aside from increased growth velocity. Recently, insulin-like growth factor-1 has gained significant attention in the understanding of growth failure in children with CF. We report the successful prolonged use of recombinant human insulin-like growth factor-1 in an adolescent boy with CF, who demonstrated significant clinical benefits from the therapy. Pediatr. Pulmonol. 2011; 46:1137-1141. (c) 2011 Wiley Periodicals, Inc.

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