Regulatory T Cell Populations in Children Are Affected by Age and Food Allergy Diagnosis

Prince, B. T.; Devonshire, A. L.; Erickson, K. A.; Bergerson, J.; Fuleihan, D.; Szychlinski, C.; Schleimer, R. P.; Bryce, P. J.; Singh, A. M.

J Allergy Clin Immunol. 2017 May 28


Young food allergic children have decreased regulatory T cell (Treg) percentages. Only Tregs from healthy controls demonstrated age-related increases in their expression of the gut-associated chemokine receptor CCR6, which may be important in maintaining oral tolerance to foods and preventing the development of allergic disease.

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