Pediatric high-grade gliomas and diffuse intrinsic pontine gliomas

Fangusaro, J.

J Child Neurol. 2009 Jul 30; 24(11):1409-17

Abstract

Pediatric high-grade gliomas represent approximately 10% of all pediatric brain tumors. Similar to adult high-grade gliomas, they behave very aggressively, and these children have a very poor prognosis despite a variety of therapies that include chemotherapy and radiotherapy. In this review, we present an overview of both pediatric high-grade gliomas and diffuse intrinsic pontine gliomas with a focus on their epidemiology, etiology, presentation, prognostic factors, biology, treatment modalities, outcomes, and future research directions.

Read More on PubMed