Patterns of Hydrocephalus Caused by Congenital Toxoplasma gondii Infection Associate With Parasite Genetics

Hutson, S. L.; Wheeler, K. M.; McLone, D.; Frim, D.; Penn, R.; Swisher, C. N.; Heydemann, P. T.; Boyer, K. M.; Noble, A. G.; Rabiah, P.; Withers, S.; Montoya, J. G.; Wroblewski, K.; Karrison, T.; Grigg, M. E.; McLeod, R.

Clin Infect Dis. 2015 Sep 26; 61(12):1831-4

Abstract

Four anatomical patterns of hydrocephalus secondary to congenital Toxoplasma gondii infection were identified and characterized for infants enrolled in the National Collaborative Chicago-based Congenital Toxoplasmosis Study. Analysis of parasite serotype revealed that different anatomical patterns associate with Type-II vs Not-Exclusively Type-II strains (NE-II) (P = .035).

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