Minimally Important Differences and Risk Levels for the Composite Asthma Severity Index

Krouse, R. Z.; Sorkness, C. A.; Wildfire, J. J.; Calatroni, A.; Gruchalla, R.; Khurana Hershey, G. K.; Kattan, M.; Liu, A. H.; Makhija, M.; Teach, S. J.; West, J. B.; Wood, R. A.; Zoratti, E. M.; Gergen, P. J.

J Allergy Clin Immunol. 2016 Oct 17


CASI is a quantitative measure of asthma severity that was introduced in the Journal of Allergy and Clinical Immunology in March 2012. This follow-up letter expands upon the initial report by comparing the CASI to an expert clinican assessment of asthma severity. Using expert assessment, we establish risk levels for CASI and calculate other useful parameters such as the minimal important difference (MID) and minimal important effect size.

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