Manifestations of bodily isomerism

Loomba, R. S.; Ahmed, M. M.; Spicer, D. E.; Backer, C. L.; Anderson, R. H.

Cardiovasc Pathol. 2016 Feb 13; 25(3):173-180


We report the findings present in 49 postmortem specimens from patients with so-called heterotaxy, concentrating on those found in the extracardiac systems of organs. Also known as bodily isomerism, we suggest that it is important to segregate the syndromes into their isomeric subtypes to be able to make inferences regarding likely extracardiac and intracardiac findings to allow for proper surveillance. We demonstrate that this is best done on the basis of the atrial appendages, which were isomeric in all the hearts obtained from the specimens available for our inspection. The abdominal organs do not demonstrate isomerism, and they show variable features when compared to the isomeric atrial appendages.

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