Genomic approaches for the discovery of CFTR regulatory elements

Ott, C. J.; Harris, A.

Transcription. 2011 Feb 18; 2(1):23-7


Non-coding regions of the human genome contain vast regulatory potential that contributes to the coordination of gene expression. Indeed, regulatory elements can reside large genomic distances from the promoters of genes they control. Here we describe approaches recently used to identify functional elements within the complex CFTR locus.

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