Defining pediatric sepsis by different criteria: Discrepancies in populations and implications for clinical practice

Weiss, S. L.; Parker, B.; Bullock, M. E.; Swartz, S.; Price, C.; Wainwright, M. S.; Goodman, D. M.

Pediatr Crit Care Med. 2012 Mar 31; 13(4):e219-26

Abstract

OBJECTIVE: : Pediatric patients with sepsis are identified using related but distinct criteria for clinical, research, and administrative purposes. The overlap between these criteria will affect the validity of extrapolating data across settings. We sought to quantify the extent of agreement among different criteria for pediatric severe sepsis/septic shock and to detect systematic differences between these cohorts. DESIGN: : Observational cohort study. SETTING: : Forty-two bed pediatric intensive care unit at an academic medical center. PATIENTS: : A total of 1,729 patients

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