Cord blood 8-isoprostane in the preterm infant

Mestan, K.; Matoba, N.; Arguelles, L.; Harvey, C.; Ernst, L. M.; Farrow, K.; Wang, X.

Early Hum Dev. 2012 Mar 20; 88(8):683-9

Abstract

BACKGROUND: Cord blood 8-isoprostane (8-IP) is a marker of lipid peroxidation in the peripartum period. The independent association with degree of prematurity is not well-described. OBJECTIVE: To identify patterns of lipid peroxidation among early, moderate and late preterm infants, and to understand how cord blood 8-IP varies with gestational age (GA) and related covariates. STUDY DESIGN: Mother-infant pairs from 237 preterm births were studied as part of a longitudinal birth cohort study. GA subgroups were defined as extremely (

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