Cognitive and academic outcomes after pediatric liver transplantation: Functional Outcomes Group (FOG) results

Sorensen, L. G.; Neighbors, K.; Martz, K.; Zelko, F.; Bucuvalas, J. C.; Alonso, E. M.

Am J Transplant. 2011 Jan 29; 11(2):303-11

Abstract

This multicenter study examined prevalence of cognitive and academic delays in children following liver transplant (LT). One hundred and forty-four patients ages 5-7 and 2 years post-LT were recruited through the SPLIT consortium and administered the Wechsler Preschool and Primary Scale of Intelligence, 3rd Edition (WPPSI-III), the Bracken Basic Concept Scale, Revised (BBCS-R), and the Wide Range Achievement Test, 4th edition (WRAT-4). Parents and teachers completed the Behavior Rating Inventory of Executive Function (BRIEF). Participants performed significantly below test norms on intelligence quotient (IQ) and achievement measures (Mean WPPSI-III Full Scale IQ = 94.7 +/- 13.5; WRAT-4 Reading = 92.7 +/- 17.2; WRAT-4 Math = 93.1 +/- 15.4; p < 0001). Twenty-six percent of patients (14% expected) had 'mild to moderate' IQ delays (Full Scale IQ = 71-85) and 4% (2% expected) had 'serious' delays (Full Scale IQ

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