Antiretroviral Drug Resistance Among Children and Youth in the United States With Perinatal HIV

Van Dyke, R. B.; Patel, K.; Kagan, R. M.; Karalius, B.; Traite, S.; Meyer, W. A., 3rd; Tassiopoulos, K. K.; Seage, G. R., 3rd; Seybolt, L. M.; Burchett, S.; Hazra, R.

Clin Infect Dis. 2016 Apr 9; 63(1):133-7


Among 234 US youths with perinatal human immunodeficiency virus, 75% had antiretroviral resistance, substantially higher than that of the reference laboratory overall (36%-44%). Resistance to newer antiretrovirals and to all antiretrovirals in a class was uncommon. The only factor independently associated with future resistance was a higher peak viral load.

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