We compare a 7-item checklist for developmental and behavioral concerns to formal screening with the Ages & Stages Questionnaires, Third Edition (ASQ-3) in children aged 1-5.5years old seen in a tertiary epilepsy care setting. The checklist was derived from a 35-item parent questionnaire used as a routine component of pediatric neuropsychology evaluations at our center. In our sample of 104 children, having even one checklist item endorsed was associated with a 97% (66/68) positive predictive value for screening positive on the ASQ-3. Fifty percent of children for whom no items were endorsed on the checklist scored negative for developmental concerns on the ASQ-3. The overall sensitivity of the checklist to a positive ASQ-3 screen was 83%, and the specificity was 88%. Use of this simple checklist may facilitate screening in the outpatient epilepsy care setting where time and resources are often limited.