Fluid Therapy and Cerebral Injury in Pediatric Diabetic Ketoacidosis

Official Title: Fluid Therapy and Cerebral Injury in Pediatric Diabetic Ketoacidosis

The investigators will conduct a randomized controlled trial comparing four different intravenous (IV) fluid treatment protocols for pediatric diabetic ketoacidosis (DKA). Two rates of rehydration will be compared; a more rapid rate and a slower rate. Within each of these two basic rehydration protocols, the investigators will vary the type of rehydration fluid used (0.9% saline or 0.45% saline). The investigators will compare the different treatments by conducting assessments of neurological injury, by measuring the frequency of significant cerebral edema, and by measuring long-term neurocognitive function.
NCT01365793
Trainor, Jennifer L., MD
Interventional
Yes

Contact Information:

Jennifer Trainor, MD

312.227.6645