This is a phase II multi-center, randomized, double blind, placebo-controlled trial.
The investigators are doing this study to see if a new drug, abatacept, can be used together with a calcineurin inhibitor (cyclosporine or tacrolimus) and methotrexate to provide better protection against Acute Graft versus Host Disease (aGvHD) without causing more infections.
Funding Source - FDA OOPD