Clinical Studies

Clinical research is very important because it is one of the best ways to improve patient care. Currently, hundreds of studies are taking place throughout Lurie Children's, including at the research institute, that involve many of our doctors, nurses, clinical research professionals, scientists and technicians.

Search below for a clinical study, or to see a more comprehensive listing of the clinical studies taking place at Lurie Children's, please use our link to the ClinicalTrials.gov website.

You can learn more about the clinical research process on our guide to clinical research for parents and children.

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Studies

Longitudinal Assessment of Transient Elastography in Cystic Fibrosis

ClinicalTrials.gov ID: NCT03001388

A noninvasive assessment of hepatic fibrosis is desperately needed to advance the care of children with CF significant liver disease and to provide for measurements during clinical trials. That global assessment might serve as both a predictor/descriptor of disease course but also as a critical biomarker for clinical research. FibroScan®...

A study in cystic fibrosis patients with chronic respiratory Pseudomonas aeruginosa infection treated with TOBI® Podhaler

ClinicalTrials.gov ID: NCT02449031

This study will include CF patients chronically colonized with P. aeruginosa enrolled in the Cystic Fibrosis Foundation (CFF) PortCF registry and using TOBI Podhaler or another FDA-approved inhaled antipseudomonal antibiotic. No therapeutic intervention will be assigned and physicians will use their discretion in choosing a treatment regimen for...

Baloxavir Marboxil in Healthy Pediatric Participants From Birth to less than 1 Year With Influenza Like Symptoms

ClinicalTrials.gov ID: NCT03653364

This is a multicenter, single-arm, open-label study to assess the safety, pharmacokinetics, and efficacy of baloxavir marboxil in otherwise healthy pediatric patients from birth to <1 year with influenza-like symptoms. Patients will be screened on Day 1 and assigned to one of three cohorts, based upon their age, to receive a single oral dose of...

Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis (PUSH)

ClinicalTrials.gov ID: NCT01144507

Advanced liver disease is a condition estimated to affect about seven percent of patients with CF, and is considered the third leasing cause of death among CF patients. There currently is no test or tool to identify CF children who are at risk of developing advanced liver disease. The aim of this study is to determine if sonographic findings...

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

ClinicalTrials.gov ID: NCT03511118

Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your medical care, at least one of the drugs we are studying. We are interested in studying drugs commonly prescribed to women who...