Clinical Studies

Clinical research is very important because it is one of the best ways to improve patient care. Currently, hundreds of studies are taking place throughout Lurie Children's, including at the research institute, that involve many of our doctors, nurses, clinical research professionals, scientists and technicians.

Search below for a clinical study, or to see a more comprehensive listing of the clinical studies taking place at Lurie Children's, please use our link to the ClinicalTrials.gov website.

You can learn more about the clinical research process on our guide to clinical research for parents and children.

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Studies

Antiviral Activity of Doses of JNJ 53718678 in Children With Respiratory Syncytial Virus Infection

ClinicalTrials.gov ID: NCT03656510

JNJ-53718678 is an investigational respiratory syncytial virus (RSV) specific fusion inhibitor and is under development for the treatment of RSV infection, which results in an upper and/or lower respiratory tract illness. The primary hypothesis of this study is that JNJ-53718678 has antiviral activity against RSV (that is, results in a decrease in...

Baloxavir Marboxil in Healthy Pediatric Participants From Birth to less than 1 Year With Influenza Like Symptoms

ClinicalTrials.gov ID: NCT03653364

This is a multicenter, single-arm, open-label study to assess the safety, pharmacokinetics, and efficacy of baloxavir marboxil in otherwise healthy pediatric patients from birth to <1 year with influenza-like symptoms. Patients will be screened on Day 1 and assigned to one of three cohorts, based upon their age, to receive a single oral dose of...

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

ClinicalTrials.gov ID: NCT03511118

Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your medical care, at least one of the drugs we are studying. We are interested in studying drugs commonly prescribed to women who...

A Pharmacokinetic Study of Tedizolid Phosphate in Pediatric Participants With Gram-Positive Infections (MK-1986-014)

ClinicalTrials.gov ID: NCT03217565

The primary objectives of this study are to describe the single-dose pharmacokinetics (PK) of intravenous (IV) tedizolid phosphate or an oral suspension of tedizolid phosphate, when administered to pediatric participants, full-term neonates, and preterm neonates.