Clinical Studies

Clinical research is very important because it is one of the best ways to improve patient care. Currently, hundreds of studies are taking place throughout Lurie Children's, including at the research institute, that involve many of our doctors, nurses, clinical research professionals, scientists and technicians.

Search below for a clinical study, or read more on our guide to clinical research for parents and children.

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A Safety and PK Study of IV Eravacycline ID: NCT03696550

This is a Phase 1, open-label, multi-center study to determine the pharmacokinetics and safety of intravenous Eravacycline in Children with Suspected or Confirmed Bacterial Infection. Male and Female subjects from 8 to less than 18 years of age who fulfill the inclusion/exclusion criteria will be enrolled in this study.

VABOMERE Meropenem-Vaborbactam in Pediatric Subjects From Birth to Less Than 18 Years of Age With Serious Bacterial Infections ID: NCT02687906

This study is an open label, dose-finding, pharmacokinetics, safety, and tolerability study of a single dose infusion of meropenem-vaborbactam in pediatric subjects from birth to less than 18 years of age with serious bacterial infections.

MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection ID: NCT03230838

This study aims to evaluate the safety and tolerability of MK-7625A (ceftolozane/tazobactam) compared with that of meropenem in pediatric participants with cUTI, including pyelonephritis.

Antiviral Activity of Doses of JNJ 53718678 in Children With Respiratory Syncytial Virus Infection ID: NCT03656510

JNJ-53718678 is an investigational respiratory syncytial virus (RSV) specific fusion inhibitor and is under development for the treatment of RSV infection, which results in an upper and/or lower respiratory tract illness. The primary hypothesis of this study is that JNJ-53718678 has antiviral activity against RSV (that is, results in a decrease in...

Baloxavir Marboxil in Healthy Pediatric Participants From Birth to less than 1 Year With Influenza Like Symptoms ID: NCT03653364

This is a multicenter, single-arm, open-label study to assess the safety, pharmacokinetics, and efficacy of baloxavir marboxil in otherwise healthy pediatric patients from birth to <1 year with influenza-like symptoms. Patients will be screened on Day 1 and assigned to one of three cohorts, based upon their age, to receive a single oral dose of...