Clinical Studies

Clinical research is very important because it is one of the best ways to improve patient care. Currently, hundreds of studies are taking place throughout Lurie Children's, including at the research institute, that involve many of our doctors, nurses, clinical research professionals, scientists and technicians.

Search below for a clinical study, or read more on our guide to clinical research for parents and children.

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Studies

Immunoablative Mini Transplant (Hematopoietic Peripheral Blood Stem Cell Transplant [HPBSC])

ClinicalTrials.gov ID: NCT00179764

The purpose of this research study is to evaluate the effectiveness of transplantation of high doses of peripheral blood stem cells (stem cells are special cells found in the blood and bone marrow that produce new blood cells) after treatment with non-myeloablative chemotherapy (not toxic to the bone marrow). In addition, this study will assess...

Cabozantinib in Treating Younger Patients With Recurrent or Refractory Solid Tumors

ClinicalTrials.gov ID: NCT01709435

This phase I trial studies the side effects and best dose of cabozantinib in treating younger patients with solid tumors that have come back or no longer respond to treatment. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Biliary Atresia Research Consortium (PROBE)

ClinicalTrials.gov ID: NCT00061828

Biliary atresia and idiopathic neonatal hepatitis are the most common causes of jaundice and hyperbilirubinemia that continue beyond the newborn period. The long term goal of the Biliary Atresia Research Consortium (BARC) is to establish a database of clinical information and serum and tissue samples from children with biliary atresia (BA) and...

Duchenne Muscular Dystrophy Tissue Bank for Exon Skipping

ClinicalTrials.gov ID: NCT01772043

We will utilize the Cooperative International Neuromuscular Research Group (CINRG) network to collect and store tissue and blood from patients with Duchenne muscular dystrophy (DMD) with specific genetic mutations within the dystrophin gene that could be treated by antisense oligonucleotide (AO) drugs.

Brentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma

ClinicalTrials.gov ID: NCT01780662

This phase I/II trial studies the side effects and the best dose of brentuximab vedotin when given together with gemcitabine hydrochloride and to see how well they work in treating younger patients with relapsed or refractory Hodgkin lymphoma. Monoclonal antibodies, such as brentuximab vedotin, can block cancer growth in different ways. Some block...