Clinical Studies

Clinical research is very important because it is one of the best ways to improve patient care. Currently, hundreds of studies are taking place throughout Lurie Children's, including at the research institute, that involve many of our doctors, nurses, clinical research professionals, scientists and technicians.

Search below for a clinical study, or read more on our guide to clinical research for parents and children.

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Open-label long term study of adjunctive brivaracetam in pediatric subjects with epilepsy ID: NCT01364597

This study will evaluate the safety and tolerability of brivaracetam in pediatric subjects with epilepsy.

HIV Prevention Intervention for Young Transgender Women (LifeSkills) ID: NCT01575938

The purpose of this study is to test the efficacy of a uniquely targeted HIV risk reduction intervention for young transgender women (YTW), ages 16 to 29, at risk for HIV acquisition or transmission.

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease ID: NCT02040714

Legg-Calvé-Perthes disease is a childhood hip disorder which is common enough to be a significant public health problem (affects 1 in 740 boys between ages 0—14), but uncommon enough to have a sufficient number of patients from a single institution to perform a definitive prospective study comparing the results of current treatments. The present...

Safety of and Immune Response to Dolutegravir (GSK1349572) in HIV-1 Infected Infants, Children, and Adolescents ID: NCT01302847

Dolutegravir (DTG) (also known as GSK1349572) is a new drug that may slow HIV replication. It works by blocking a protein named integrase, which HIV needs in order to make copies of itself in the human body. This drug has been tested for safety and effectiveness in adults but not in children. This study will test the safety of and immune response...

Multi-institutional Trial of Non-operative Management of Appendicitis ID: NCT02271932

A successful non-operative management strategy for early appendicitis will decrease the number of children requiring surgery and may improve the quality of care related to the treatment of appendicitis. To account for the child-family perspective and treatment preferences, the investigators will perform a study in which patients and their families...