Clinical Studies

Clinical research is very important because it is one of the best ways to improve patient care. Currently, hundreds of studies are taking place throughout Lurie Children's, including at the research institute, that involve many of our doctors, nurses, clinical research professionals, scientists and technicians.

Search below for a clinical study, or read more on our guide to clinical research for parents and children.

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Studies

INFUSE Bone Graft (recombinant human Bone Morphogenetic Protein-2/absorable collegen sponge) in the treatment of Tibial Psudarthrosis in Neurofibromatosis 1 (NF1)

ClinicalTrials.gov ID: NCT02718131

The current study proposes adding BMP-2 (INFUSE), an anabolic agent, at the surgical site of TPA repair in children with NF1, compared to a control group of patients treated surgically without BMP-2. The following Specific Aims will be addressed: 1) to determine if use of an osteogenic agent (BMP-2) at the time of surgical repair of TPA in NF1...

IMPAACT P1115 Very Early Intensive Treatment of HIV-Infected Infants to Achieve HIV Remission

IMPAACT P1115 will explore the effects of early intensive antiretroviral therapy (ART) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among HIV-infected infants.

Slide Alone: Fracture Prevention in Toddlers and Youth (SAFETY)

This study will examine children diagnosed with a fracture that occurred while using a playground slide in order to understand the causes of these injuries.

A Study of Intravenous Isavuconazonium Sulfate in Pediatric Patients

ClinicalTrials.gov ID: NCT03241550

The purpose of the study is to evaluate the pharmacokinetics (PK), safety and tolerability of multiple doses of intravenous (IV) isavuconazonium sulfate administered daily in pediatric patients. The PK data will be utilized to establish a pediatric population PK model of isavuconazole, the active moiety of isavuconazonium sulfate.

Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or Disease

ClinicalTrials.gov ID: NCT 02596997

Provide patients with serious AdV infection or disease access to treatment with BCV