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Clinical Studies

Clinical research is very important because it is one of the best ways to improve patient care. Currently, hundreds of studies are taking place throughout Lurie Children's, including at the research institute, that involve many of our doctors, nurses, clinical research professionals, scientists and technicians.

Search below for a clinical study, or to see a more comprehensive listing of the clinical studies taking place at Lurie Children's, please use our link to the ClinicalTrials.gov website.

You can learn more about the clinical research process on our guide to clinical research for parents and children.

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Studies

Tiny Cargo, Big Deal! An ED-Based Study of Child Passenger Safety Behaviors

ClinicalTrials.gov ID: NCT04238247

Motor vehicle collisions remain the leading cause of unintentional injury deaths among children in the United States despite the availability of car seats and booster seats that are effective in preventing injuries. Some communities are disproportionately impacted by deaths in crashes because of suboptimal child passenger safety behaviors. This...

Improving Medication Adherence in Adolescents Who Had a Liver Transplant (iMALT)

ClinicalTrials.gov ID: NCT03691220

Pediatric adolescent and young adult (age at enrollment ≥12 and < 18) transplant recipients will be eligible for participation in the study. Learn more.

Open-label Access to Dolutegravir for HIV-1 Infected Children and Adolescents Completing IMPAACT Studies P1093 and P2019

ClinicalTrials.gov ID: NCT03016533

To assess the pharmacokinetics (PK), safety, and tolerability of fixed dose combination abacavir (ABC)/ dolutegravir (DTG)/ lamivudine (3TC) in HIV-1-infected children.

The Pediatric ALL Evaluation and Trial (PALLET): A Randomized, Controlled Trial

Studies have shown the rising incidence of anterior cruciate ligament (ACL) injuries in children and adolescents. Pediatric patients are at a higher risk of graft failure than adults (3-4% compared to 12-19%) after ACL reconstruction. In the adult population, a growing number of studies have suggested that concomitant reconstruction of the...

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

ClinicalTrials.gov ID: NCT04322708

This is a Phase 2/3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002) given monthly for 6 doses in adult and adolescent patients with active eosinophilic esophagitis. Subjects who complete the randomized, double-blind, placebo-controlled treatment may have the option to...