Clinical Studies

Clinical research is very important because it is one of the best ways to improve patient care. Currently, hundreds of studies are taking place throughout Lurie Children's, including at the research institute, that involve many of our doctors, nurses, clinical research professionals, scientists and technicians.

Search below for a clinical study, or read more on our guide to clinical research for parents and children.

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Studies

A Two-Part Multicenter Prospective Longitudinal Study of CFTR-dependent Disease Profiling in Cystic Fibrosis (PROSPECT)

ClinicalTrials.gov ID: NCT02477319

Identify and validate biomarkers that might reflect partial restoration of CFTR function and can be used to monitor disease progression, and ii) evaluate the mechanistic effects of CFTR modulators and...

Study of Ataluren in Nonsense Mutation Cystic Fibrosis (ACT CF)

ClinicalTrials.gov ID: NCT02139306

This is a Phase 3, international, multicenter, randomized, double-blind, placebo-controlled, efficacy and safety study of ataluren in patients with nonsense mutation cystic fibrosis (nmCF) not receivi...

Haplo-identical SCT for HR Hematologic Malignancies w/Post-Transplant In-Vivo T-cell Depletion

ClinicalTrials.gov ID: NCT02053545

Although a majority of children with leukemia and most hematological malignancies (Hodgkin's and Non-Hodgkin's lymphomas) can be cured with conventional chemotherapy, a subset of patients with resista...

The Pediatric Anesthesia Quality Improvement Project

ClinicalTrials.gov ID: NCT00674388

The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthestics...

Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease (HaploSCD)

ClinicalTrials.gov ID: NCT01461837

The purpose of this study is to investigate host myeloimmunosuppressive conditioning followed by familial haploidentical T cell depleted allogeneic stem cell transplantation in patients with high risk...