Nicholas Katsanis, PhD

Nicholas (Nico) Katsanis obtained his Baccalaureate degree in Genetics from University College London in 1993 and his Doctorate degree from Imperial College London in 1997. 

While at Imperial College, he worked with Dr. Elizabeth Fisher on the genetics of Down syndrome. He completed his postdoctoral work in the laboratory of Dr. James Lupski within the Department of Molecular and Human Genetics at Baylor College of Medicine in Houston and transitioned his studies to Bardet-Biedl syndrome.   

In 2002, he established his independent research lab at the Institute of Genetic Medicine, Johns Hopkins University, where he led studies that unified several allied conditions under the ciliopathy umbrella. Dr. Katsanis demonstrated that Bardet-Biedl syndrome is caused by centrosomal/basal body dysfunction, establishing that dysfunction at the primary cilium can give rise to a large group of disorders with both clinical and genetic overlap (the ciliopathy model). 

In 2009, he moved to Duke University to establish the Center for Human Disease Modeling (CHDM). During his decade at Duke, he developed a structure that aimed to facilitate collaboration across disciplines and to develop physiologically relevant tools to study variation found in human patient genomes. To build upon the strong foundation of assay development and multidisciplinary research developed at the CHDM, Dr. Katsanis was recruited to the Stanley Manne Children’s Research Institute at the Lurie Children’s Hospital of Chicago in 2019. He is the Director of the Advanced Center for Translational and Genetic Medicine (ACT-GeM); Associate Chief Research Officer for Translational Research; and Head of the Human Molecular Genetics and Physiology Neighborhood.

Dr. Katsanis has longstanding interests in the strategic discovery of genes critical for neonatal/perinatal development; context dependent analysis of genomes; and parallelization of approaches to therapeutics.

In recognition of his work, Dr. Katsanis was awarded the Young Investigator Award from the American Society of Nephrology in 2009, the E. Mead Johnson Award from the Society for Pediatric Research in 2012, the Curt Stern Award from the American Society of Human Genetics in 2017 and has delivered several distinguished lectures. Dr. Katsanis is Professor in the Departments of Pediatrics and Cell & Molecular Biology at the Northwestern University Feinberg School of Medicine and holds the Valerie and George D. Kennedy Professorship of Human Genetics.

Dr. Katsanis has mentored more than 60 predoctoral and postdoctoral trainees and has demonstrated a significant commitment to training physician-scientists. 

He has published over 300 research papers, reviews, and book chapters; serves on several advisory, editorial, and organizational boards; and has delivered over 250 lectures in 40 countries. Visit Google Scholar for a complete listing of Dr. Katsanis' publications.