Scientist's Artwork Featured on Journal Cover

September 17, 2018

Kohtz cover artworkA stunning image of a sunflower - painted by Jhumku Kohtz, PhD - is featured on the cover of Molecular Cell, September 20, 2018. The cover art accompanies an article in the issue authored by Kohtz, postdoctoral associate Ivelisse Cajigas, PhD, and others. A press release about this publication was issued in August 2018.

Kohtz is Research Professor of Pediatrics - Developmental Behavioral Pediatrics - at Northwestern University Feinberg School of Medicine, and director of a laboratory at Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago.

As described by the journal:

"On the cover: In this issue of Molecular Cell, Cajigas et al. (pp. 956–972) describe a mechanism whereby an enhancer lncRNA organizes distant genes involved in mammalian forebrain development. The inflorescence of the sunflower represents the “cloud” formed by the lncRNA, which organizes diverse proteins, the enhancer encoding the lncRNA, target genes, and chromatin. The outer ray petals represent the chromatin loops surrounding the cloud, which form between genes contacted by the enhancer."

Full citation of the article: The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain. bIvelisse Cajigas, Abhijit Chakraborty, Kelsey R. Swyter, Hao Luo, Monique Bastidas, Maximilliano Nigro, Elizabeth R. Morris, Sean Chen, Michael J.W. VanGompel, David Leib, Sara J. Kohtz, Marco Martina, Sooky Koh, Ferhat Ay, Jhumku D. Kohtz. Molecular Cell 2018: v. 71(6): 956-972.