Evidence-Based Practice

Lurie Children’s Paediatric Research & Evidence Synthesis Centre of Innovative Implementation Science & Engagement (PRESCIISE) advances our vision to provide the best care and experience to every child by supporting collaboration, evaluating evidence, translating knowledge, innovating & transforming healthcare. Our specialty is paediatric evidence-based health and healthcare. Our goal is to make sure children, families, and communities have access to evidence and evidence-based care that engages stakeholders to preciisely meet children’s health, wellness, disease prevention and management, including symptom-management and self-management needs.

Lurie Children’s is committed to exemplary interprofessional clinical practice, structural empowerment, knowledge generation, innovation, evidence-based care, empirical evidence of quality care improvement, and transformational leadership. Lurie Children’s PRESCIISE conducts systematic reviews, provides education and coaching to stakeholders in JBI systematic review methods and model for incorporating evidence into clinical practice. PRESCIISE engages staff, academic affiliations, collaborators, professional societies, public and private organizations and funders to (1) provide the best care and patient-family experiences, (2) advance paediatric medicine and science, (3) care for more children, and (4) be the healthcare employer of choice. Fueled by JBI’s model of evidence-based healthcare, training programs, tools, and global collaboration, PRESCIISE effectively contributes to advancing quality outcomes of paediatric healthcare regionally and globally as a recognized leader and source for paediatric evidence-based care and implementation science that transforms the future of children’s health.

Director/Convenor: Dr. Renee CB Manworren, PhD, APRN, PCNS-BC, AP-PMN, FAAN

Deputy Directors: Dr. Karen Carroll, PhD, RN, NEA-BC & Dr. Lauren Sorce, PhD, APRN, CPNP-AC/PC, FCCM

Administrative Assistant: Sameerah Miller, 312.227.5496, Shmiller@luriechildrens.org

Librarian: Andrea Fawcett, MLIS

Physician Partner: Maria Rahmandar, MD

Evidence-based practice strategist: Inga Uremovich, MSN, RN, CPN

Evidence-based practice fellows: Michelle High, MSN, RN, CNL, CPN & Eileen Romano, BSN, MBA, RN, CENP


Registered systematic review protocols:

Scoping review of EBP implementation infrastructure: Karen Carroll, PhD, RN, Peggy Murphy, MLIS, Eileen Romano MBA, RN & Inga Uremovich, MS, RN

From prescribed opioid use for acute pain to misuse and substance use disorder as adolescents and young adults: A Systematic Review Renee Manworren, PhD, APRN, FAAN, Maria Rahmander, MD, & Andrea Fawcett, MLIS PROSPERO 2020 CRD42020179635

Effectiveness of IV lidocaine to treat acute vaso-occlusive pain from sickle cell disease: An effectiveness Systematic Review Protocol. Emily Wilt, Peggy Murphy, MLIS, & Renee Manworren, PhD, APRN, FAAN. PROSPERO 2020 CRD42020199951

Safety and effectiveness of muscle relaxants on postoperative pain: A Systematic Review Protocol., Marit Lyons, Renee Manworren, PhD, APRN, FAAN Jennifer Fanelli, MS, APRN, CPNP, & Peggy Murphy, MLIS PROSPERO 2020 CRD42020206422