For Healthcare ProfessionalsCenter for Advanced Practice Academic & Professional Excellence
Academic & Professional Excellence
Nursing Research
Lauren R. Sorce, PhD, RN, CPNP-AC/PC, FCCM, FAAN
Senior Director of Nursing Research and Operations, Department of Nursing and Stanley Manne Children’s Research Institute; Senior Scientist, Division of Pediatric Critical Care; Pediatric Critical Care Nurse Practitioner
Dr. Sorce leads strategic planning and execution of nursing research initiatives and clinical trial protocols across the Lurie Children’s enterprise. Dr Sorce oversees the strategic direction, coordination, and advancement of clinical research nursing and drives operational excellence, ensuring regulatory and protocol compliance, and fostering a culture of innovation and integrity in clinical trial delivery throughout the medical center. She supports investigator-initiated and industry-sponsored research efforts, while strengthening the integration of nursing within the broader research enterprise.
Professional Leadership
Many of the Lurie Children's APPs hold offices in local and national professional organizations, participate and lead in hospital and community committees, support legislative advocacy, and have received national awards related to improving the delivery of quality, safe and effective patient care to our specialized pediatric populations.
Publications & Presentations
Lurie Children's APPs advance pediatric research and science through publication and podium presentations at state, national, and international conferences. APPs are empowered to lead, learn, and contribute meaningfully to evidence-based pediatric care.
One on one mentorship is available to support scholarly activity including quality projects and research initiatives. The institution maintains its own Institutional Review Board (IRB), ensuring rigorous ethical oversight for all research.
APP Publications
APPs are actively involved in research. They lead projects, serve as PIs, and site PIs for multicenter studies, and participate in a wide variety of research. See below highlighted APP publications.
Yang MM, Singh R, Haugen M, et al. Adherence to 6-Mercaptopurine (6-MP) and Habit Strength in Pediatric Acute Lymphoblastic Leukemia (ALL). Article. Eur J Haematol. 2025;doi:10.1111/ejh.14386
Wong J, Loomba R, Allen KY, et al. Structured Tube Weaning Using the Hunger Provocation Method in Infants with Single Ventricle Heart Defects: A Multicenter Study. Article. Pediatric Cardiology. 2025;46(5):1372-1380. 101406. doi:10.1007/s00246-024-03558-x
Watson RS, Argent AC, Sorce LR, et al. The 2024 Phoenix Sepsis Score Criteria: Part 1, the Evolution in Definition of Sepsis and Septic Shock. Conference Paper. Pediatr Crit Care Med. 2025;26(2):e246-e251. doi:10.1097/PCC.0000000000003664
Strine S, Karuri S, Fry JT, Bean K, Horner S, Machut KZ. Culture of Family-Centered Care in the NICU. Article. Advances in Neonatal Care. 2025;10.1097/anc.0000000000001249. doi:10.1097/ANC.0000000000001249
Sorce LR, Asaro LA, Curley MAQ, for the RSI. Infant feeding and criticality in children. Article. Nursing in Critical Care. 2025;30(2)e13103. doi:10.1111/nicc.13103
Rosenblatt A, Dominguez-Cancino K, Chung C, et al. Mapping resilience and co-occurring theoretical constructs in nurses: a scoping review protocol. Article. JBI Evidence Synthesis. 2025;23(5):975-982. doi:10.11124/JBIES-24-00342
Randolph AG, Hall MW, Kissoon N, et al. The 2024 Phoenix Sepsis Score Criteria: Part 5, What About "Parsimony" in the Criteria - Is Less Really More? Conference Paper. Pediatr Crit Care Med. 2025;26(2):e266-e271. doi:10.1097/PCC.0000000000003665
Naureckas Li C, Heald-Sargent T, Murtagh K, Claussen E, Jhaveri R. Billing for and Documentation of Provider-to-Provider Interprofessional Consults in Infectious Diseases. Article. J Pediatric Infect Dis Soc. 2025;14(5)piaf033. doi:10.1093/jpids/piaf033
Martin S. A Pediatric Nurse's Plea for Help with the Firearm Epidemic. Short Survey. Am J Nurs. 2025;125(4):9. doi:10.1097/AJN.0000000000000042
Lim MJ, Whitney JE, Sallee CJ, et al. Plasma Soluble Intercellular Adhesion Molecule-1 Has a Central Role in Biomarker Network Analysis and Is Associated With Poor Outcomes in Two Distinct Pediatric Cohorts of Acute Respiratory Distress Syndrome and Acute Respiratory Failure. Article. Critical Care Medicine. 2025;10.1097/ccm.0000000000006719. doi:10.1097/CCM.0000000000006719
Harding CO, Arnold G, Berry GT, et al. Phenylketonuria in adults: we know plenty, but there is much more to learn. Letter. Am J Clin Nutr. 2025;121(3):741-743. doi:10.1016/j.ajcnut.2024.12.024
Frank DU, Kasmai CT, Winder MM, et al. Refractory Chylothorax: Descriptive Analysis and Predictive Model in Children with Postoperative Chylothorax. Article. Pediatric Cardiology. 2025;doi:10.1007/s00246-025-03807-7
Cooney E, Ammous Z, Bender T, et al. Lessons learned from 5 years of pegvaliase in US clinics: A case series. Article. Mol Genet Metab Rep. 2025;42101181. doi:10.1016/j.ymgmr.2024.101181
Bieber D, Gupta K, Abdallah R, et al. Development of an Educational Curriculum for Implanting and Managing Vagus Nerve Stimulators for Epilepsy. Article. Neuromodulation. 2025;28(4):551-557. doi:10.1016/j.neurom.2024.12.008
Afseth C, Knutsen J, Lamborn T, et al. Evaluating the Influence of Social Determinants of Health on Blood Phenylalanine Levels in Phenylketonuria Patients. Article. Am J Med Genet Part A. 2025;197(2)e63885. doi:10.1002/ajmg.a.63885
Winder MM, Schwartz S, Buckley JR, et al. Optimal Fat-Modified Diet Duration for the Treatment of Postoperative Chylothorax in Children. Article. Ann Thorac Surg. 2024;118(1):181-187. doi:10.1016/j.athoracsur.2023.05.021
Watson RS, Schlapbach LJ, Sorce LR. Pediatric Phoenix Sepsis Score Validation Challenges in Low-Resource Settings and in the Emergency Department - Reply. Letter. JAMA. 2024;331(24):2135-2136. doi:10.1001/jama.2024.8447
Wang AP, Khan H, Dong S, et al. Primary Adjunctive Corticosteroids in the Acute Management of High-Risk Kawasaki Disease in a North American Cohort. Article. J Pediatric Infect Dis Soc. 2024;13(12):626-632. doi:10.1093/jpids/piae112
Vucko E, Baker J, Becker K, Havens K, Arduini K, Shim S. Management of a urea cycle disorder in the setting of socioeconomic and language barriers. Article. Mol Genet Metab Rep. 2024;39101108. doi:10.1016/j.ymgmr.2024.101108
Vogel C, Hinkle C, Cassedy A, et al. Motor proficiency in school-aged children with CHD. Article. Cardiol Young. 2024;doi:10.1017/S1047951124026763
Toia J, Murtagh K, Heald L, Leake K, Jhaveri R. Advanced Practice Providers in Pediatric Infectious Diseases. Review. J Pediatric Infect Dis Soc. 2024;13(3):228-231. doi:10.1093/jpids/piae008
Tager JB, Hinojosa JT, Liabraaten BM, et al. Challenges of Families of Patients Hospitalized in the PICU: A Preplanned Secondary Analysis from the Navigate Dataset∗. Article. Pediatr Crit Care Med. 2024;25(2):128-138. doi:10.1097/PCC.0000000000003385
Szmuilowicz ED, Fruzyna E, Madden N, et al. Management of Dysglycemia in a Pregnancy Complicated by Fanconi–Bickel Syndrome. Article. AACE Clin Case Rep. 2024;10(6):224-228. doi:10.1016/j.aace.2024.07.008
Sorce LR. Society of Critical Care Medicine Presidential Address-53rd Annual Congress, January 2024. Article. Critical Care Medicine. 2024;52(6):863-868. doi:10.1097/CCM.0000000000006282
Schlapbach LJ, Watson RS, Sorce LR, et al. International Consensus Criteria for Pediatric Sepsis and Septic Shock. Article. JAMA. 2024;331(8):665-674. doi:10.1001/jama.2024.0179
Sanchez-Pinto LN, Bennett TD, Dewitt PE, et al. Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. Article. JAMA. 2024;331(8):675-686. doi:10.1001/jama.2024.0196
Rosenblatt A, Pederson R, Davis-Sandfoss T, Irwin L, Mitsos R, Manworren R. Child life specialist services, practice, and utilization across health care: A scoping review. Article. JBI Evidence Synthesis. 2024;22(7):1303-1328. doi:10.11124/JBIES-23-00025