Nicholas R. Zessis, MD

Attending Physician, Hospital-Based Medicine

Assistant Professor of Pediatrics (Hospital-Based Medicine), Northwestern University Feinberg School of Medicine



Ann & Robert H. Lurie Children's Hospital of Chicago

225 E. Chicago Ave.
Chicago, Illinois 60611

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Prentice Women's Hospital at Northwestern Medicine

250 E. Superior Street
Chicago, Illinois 60611

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Dr. Zessis is a hospital pediatrician at Lurie Children's. His academic and clinical interests include Hospital Medicine on the medical floor and intensive care unit, medical education, quality improvement, and advocacy. He is a member of the Feinberg Academy of Medical Educators.

Clinical Interests

Hospital-based medicine, general pediatrics, complex care, COVID-19, quality improvement, underserved medicine

Education & Training

Education: Northwestern University Feinberg School of Medicine, 2016

Postgraduate Training: Residency in pediatrics, Washington University School of Medicine, 2016-2019

Board Certifications: Pediatrics

Professional Organizations: Feinberg Academy of Medical Educators

Research & Publications


Zessis NR, Sadanand A, Reis A, Cole JJ, Mammel DM, Hrach C, Daud YN. “Smartphone-Based Teaching App Increases Frequency of Residents Teaching Medical Students.” Abstract published at Society of Hospital Medicine 2019, March 25, 2019, National Harbor, MD. Abstract 101.

Zessis NR, Gao F, Vadlamudi G, Gutmann DH, Hollander AS. “Height growth impairment in children with Neurofibromatosis Type 1 is characterized by a decreased pubertal growth velocity in both sexes.” J Child Neurol 2018; 33:12. DOI: 10.1177/0883073818786807.

Zessis NR, Nicholas JL, Stone SI. “Severe bilateral adrenal hemorrhages in a newborn complicated by persistent adrenal insufficiency.” Endocrinol Diabetes Metab Case Rep 2018; 20:17-0165. DOI: 10.1530/EDM-17-0165

Zessis NR, Holly TA, Wu E. “Development and comparison of accelerated diagnostic chest pain protocols to predict a low-likelihood in developing acute coronary syndrome within six hours.” Journal of the American College of Cardiology Apr 2016, 67 (13) 514. DOI: 10.1016/S0735-1097(16)30515-0.

Teaching scripts via smartphone app facilitate resident-led teaching of medical students.
Zessis NR, Dube AR, Sadanand A, Cole JJ, Hrach CM, Daud YN
BMC Med Educ. 2021 Jun; 21(1): 331-.
PMID: 34103029

A Shower an Hour
Zessis N
Pediatric Diagnostic Medicine. 2021 Sep;
ISBN: 9781975159474