Simone T. Sredni, MD, PhD

Research Associate Professor of Neurological Surgery, Northwestern University Feinberg School of Medicine

Director, Initiative for the Study and Translational ATRT Research (iSTAR AT/RT), Stanley Manne Children's Research Institute

Education & Training

Education: Santa Casa Medical School, São Paulo, Brazil, 1990,

Postgraduate Training: University of São Paulo, Brazil, Pathology, 1999

Research

Research Interests: Cancer biology; cancer genetics; cancer: pediatric non-sarcoma solid tumors; pediatric embryonal tumors; rhabdoid tumors; AT/RT; cancer: brain and nervous system; cancer: genomics; pathology

Publications

Most recent publications

Extensive miRNA expression analysis in craniopharyngiomas Childs Nerv Syst32 (9): 1617-24
Histone deacetylases expression in atypical teratoid rhabdoid tumors Childs Nerv Syst29 (1): 5-9
A Parallel Study of mRNA and microRNA Profiling of Peripheral Blood in Young Adult Women Front Genet249
Identification of MicroRNAs as Potential Prognostic Markers in Ependymoma PLoS One6 (10): e25114
Molecular profiling of isolated histological components of wilms tumor implicates a common role for the Wnt signaling pathway in kidney and tumor development Oncology75 (1-2): 81-91
The polo-like kinase 4 gene (PLK4) is overexpressed in pediatric medulloblastoma Childs Nerv Syst33 (7): 1031
MicroRNA-10a Regulation of Proinflammatory Mediators: An Important Component of Untreated Juvenile Dermatomyositis J Rheumatol43 (1): 161-8
A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells PLoS One10 (3): e0121707
Study of the gene expression and microRNA expression profiles of malignant rhabdoid tumors originated in the brain (AT/RT) and in the kidney (RTK) Childs Nerv Syst29 (11): 1977-83
Predicting relapse in favorable histology Wilms tumor using gene expression analysis: a report from the Renal Tumor Committee of the Children's Oncology Group Clin Cancer Res15 (5): 1770-8

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News

2 Results

New Potential Treatment for Aggressive Brain Cancer in Children

Promising Target for Treating Brain Tumors in Children

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