Paul T. Schumacker, PhD

Professor of Pediatrics, Cell and Molecular Biology, and Medicine, Northwestern University Feinberg School of Medicine

Associate Director, Pediatric Research; Patrick M. Magoon Distinguished Professor of Neonatal Research

Education & Training

Education: ,

Postgraduate Training: Albany Medical College, Albany, NY, Physiology, 1980

Research

Research Interests: Cancer biology; cardiovascular diseases; cell biology; lungs, breathing problems; metabolism; pulmonary hypertension; signal transduction

Publications

Most recent publications

JNK2 Upregulates Hypoxia-Inducible Factors and Contributes to Hypoxia-Induced Erythropoiesis and Pulmonary Hypertension J Biol Chem
JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension J Biol Chem293 (1): 271-284
Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress Hum Mol Genet26 (10): 1915-1926
MicroRNAs and PARP: co-conspirators with ROS in pulmonary hypertension. Focus on "miR-223 reverses experimental pulmonary arterial hypertension" Am J Physiol Cell Physiol309 (6): C361-2
Hypoxia inducible factor signaling and experimental persistent pulmonary hypertension of the newborn Front Pharmacol647
Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel? Nat Rev Cancer14 (11): 709-21
Mitochondria-targeted Ogg1 and Aconitase-2 Prevent Oxidant-induced Mitochondrial DNA Damage in Alveolar Epithelial Cells J Biol Chem289 (9): 6165-76
Paradoxical Regulation of Hypoxia Inducible Factor-1alpha (HIF-1alpha) by Histone Deacetylase Inhibitor in Diffuse Large B-Cell Lymphoma PLoS One8 (11): e81333
Regulation of Hypoxia-induced Pulmonary Hypertension by Vascular Smooth Muscle Hypoxia-Inducible Factor-1alpha Am J Respir Crit Care Med189 (3): 314-24
Unraveling the biological roles of reactive oxygen species Cell Metab13 (4): 361-6

Paul T. Schumacker, PhD

Paul T. Schumacker, PhD

Professor of Pediatrics, Cell and Molecular Biology, and Medicine, Northwestern University Feinberg School of Medicine

Associate Director, Pediatric Research; Patrick M. Magoon Distinguished Professor of Neonatal Research

Education & Training

Research

Publications

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