Isabelle De Plaen, MD

Attending Physician, Neonatology

Associate Professor of Pediatrics-Neonatology, Northwestern University Feinberg School of Medicine

Language: English

Appointments & Referrals

1.800.543.7362 (1.800.KIDS DOC)

About Me

Clinical Interests: Mechanisms of gut injury-necrotizing enterocolitis

Specialties, Programs & Conditions

Specialties:

Neonatology

Education & Training

Education: Catholic University of Louvain School of Medicine, Brussels, Belgium, 1989

Postgraduate Training: Northwestern University Medical School, 1998; Catholic University of Louvain School of Medicine, Brussels, Belgium, 1995; California Pacific Medical Center, Children's Hospital, San Francisco, 1994

Board Certifications: Neonatal-Perinatal Medicine, General Pediatrics

Research

Research Interests: Cytokines; Digestive System (including gallbladder and liver); Immunology; Necrotizing Enterocolitis; Neonatal Necrotizing Entercolitis; Pediatrics

Publications

Prenatal inflammation impairs intestinal microvascular development through a TNF-dependent mechanism and predisposes newborn mice to necrotizing enterocolitis
Am J Physiol Gastrointest Liver Physiol317 (1): G57-g66
Blocking NF-kappaB Activation in Ly6c(+) Monocytes Attenuates Necrotizing Enterocolitis
Am J Pathol189 (3): 604-618
Intestinal microcirculation and necrotizing enterocolitis: The vascular endothelial growth factor system
Semin Fetal Neonatal Med23 (6): 411-415
In Inflamed Intestinal Tissues and Epithelial Cells, Interleukin 22 Signaling Increases Expression of H19 Long Noncoding RNA, Which Promotes Mucosal Regeneration
Gastroenterology155 (1): 144-155
Dimethyloxalylglycine preserves the intestinal microvasculature and protects against intestinal injury in a neonatal mouse NEC model: role of VEGF signaling
Pediatr Res

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