Research Programs

The research programs at Stanley Manne Children’s Research Institute support the clinical mission of Lurie Children’s by providing an environment that encourages scientists to ask and answer fundamental questions about children’s health. New medical therapies are based on the foundation of scientific discovery. The common bonds uniting the researchers are their curiosity about the origins and mechanisms of disease, their search for cures and therapies, and their strong desire to transform medicine. The scientific breakthroughs by our multidisciplinary teams of researchers make a difference in the lives of children and their families.

Manne Research Institute’s programs are comprised of six robust and complex groups that focus on scientific, translational medicine and children’s health research:

Cancer Biology & Epigenomics Program

This program focuses on:

  • Identification of molecular mechanisms underlying tumorigenesis, metastasis and development of drug resistance
  • Affiliated with the Falk Brain Tumor Center

Learn more about our Cancer Biology and Epigenomics Program.

Clinical & Translational Research Program

This program strives to:

  • Accelerate the delivery of new therapies and cures to children through clinical and translational research at Lurie Children's
  • Be a resource for training, continuing education and research support
  • Develop a culture of research at Lurie Children's, learn from our patients and improve health outcomes

Learn more about our Clinical and Translational Research Program.

Developmental Biology Program

This program focuses on:

  • Mechanisms of genetic fate in early human development
  • Directing the Fish Facility and the Human iPS & Stem Cell Core

Learn more about our Developmental Biology Program.

Human Molecular Genetics Program

This program works on:

  • Translational genetic medicine, with innovative basic science aimed at generating new routes to therapy for inherited diseases
  • Is a member of the Northwestern University genetics and genomics community

Learn more about our Human Molecular Genetics Program.

Mary Ann & J. Milburn Smith Child Health Research Program

The Smith Child Health Research Program aims to:

Learn more about the Smith Child Health Research Program.

Neurobiology Program

This program researches:

  • Molecular processes critical to development, degeneration and regeneration of cells in the nervous system
  • Development of novel therapies for neurological diseases and injuries

Learn more about our Neurobiology Program.

In addition to these programs, the Manne Research Institute Training Program is a dedicated and distinguished endeavor, developing outstanding graduate and post-graduate scientists for their careers. Not only does the training prepare them for individual success, but under the guidance of our faculty members, the students and fellows contribute breakthrough research and technologies that aid in the application of basic science discoveries to clinical practice.

Graduate and Postdoctoral Training Program

This program:

  • Develops outstanding graduate and post-graduate scientists for their careers
  • Encourages trainees to contribute to breakthrough research and technologies
  • Offers leadership roles for trainees to present, plan events and collaborate

Learn more about our Graduate and Postdoctoral Training Program.