Pediatric Stem Cell Transplant Program

Since 1992, our Pediatric Stem Cell Transplant Program, has performed more than 1,000 stem cell transplants, making it one of the nation's largest pediatric programs of its kind. It is a part of the Center for Cancer and Blood Disorders, which is ranked 12th in the nation by U.S.News & World Report for pediatric oncology; the program is also a part of the Siragusa Transplantation Center. As the first freestanding pediatric
program to earn accreditation from the Foundation for the Accreditation of Cellular Therapy, the program is recognized for its quality, outcomes, multidisciplinary approach to care, research and laboratory expertise. We offer several comprehensive, multidisciplinary specialty clinics, including chronic graft vs. host disease, immune deficiency, long term follow-up and bone marrow failure​.

The Lurie Children’s Difference

  • Our program is accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) in the areas of pediatric autologous transplant, allogeneic transplant, marrow collection and peripheral blood by apheresis collection.
  • Our Ambulatory Infusion Center provides comprehensive outpatient treatment, including family-friendly hours, to hematology, oncology and stem cell transplant patients.
  • We offer our patients access to in-house protocols and national studies.
  • Hospital-wide collaboration means that newborns identified with immune deficiencies in the Newborn Screening Center are quickly referred to and treated by immunologists and stem cell transplant specialists.
  • We are a member of the Primary Immune Deficiency Treatment Consortium (PIDTC), a group of 13 major centers in North America collaborating to improve the outcome of patients with rare, life threatening, inherited disorders of the immune system.


During a pediatric stem cell transplant, a patient's diseased or damaged bone marrow is replaced with healthy blood stem cells. Patients first receive chemotherapy and/or radiation to eliminate diseased cells and make space in the bone marrow. The stem cells are then infused and make their way to the space in the bone marrow, and start producing healthy blood cells.

All children referred for a stem cell transplant at Lurie Children's have a multidisciplinary team to support them before and after transplant. Patients and their families benefit from this tight team approach, which combines highly-specialized training and clinical expertise of all stem cell transplant specialists. The goal of this team approach is to provide consistent, expert care from the point of referral to the completion of the transplant.


The team includes:

  • Specialized physicians with extensive training and experience in stem cell transplantation
  • Advanced practice nurses (APNs) who work with physicians as part of the dedicated primary team, caring for the child throughout the transplant process.
  • Nurses that are trained to care for pediatric patients undergoing transplant.
  • A social worker and a psychosocial expert work as a team with child life specialists​ to support the emotional, social, educational and developmental needs of the patient and family
  • A financial coordinator helps patient families navigate financial and insurance issues.
  • A specialized pharmacist is dedicated to managing medications for transplant patients.

The status of patients preparing for a stem cell transplant is reviewed in dedicated meetings. Team members discuss diagnosis, transplant and donor options and treatment regimens. They also review any insurance, financial, family or cultural concerns.

Make an Appointment

If you’d like to request an appointment with one of our specialists, call 1.800.543.7362 (1.800.KIDS DOC®). You can also request an appointment online.


Your support is important in helping us continue to make a difference in the lives of patients and families. Lurie Children’s relies on philanthropic funding to enhance its programs, services and research for children. To learn more, please contact the Ann & Robert H. Lurie Children’s Hospital of Chicago Foundation at, call 312.227.7500 or make a gift today.


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​Transitioning to Home Care

Almost Home Kids (AHK), now part of the Lurie Children’s family, cares for children with complicated health needs by providing family training, respite care and short-term transitional care in a home-like setting. AHK is staffed with medical professionals and volunteers to make sure every child and their families are prepared for the return home. The Stem Cell Transplantation Program works closely with Almost Home Kids to make the care transition process as easy as possible.

Learn more about AHK.