Pediatric Stem Cell Transplant Program

Since 1992, our Pediatric Stem Cell Transplant Program, which is part of the Siragusa Transplantation Center, has performed more than 1,000 stem cell transplants, making it one of the nation's largest pediatric programs. As the first freestanding pediatric program to earn accreditation from the Foundation for the Accreditation of Cellular Therapy, the program is recognized for its quality, outcomes, multidisciplinary approach to care, research and laboratory expertise. We offer several comprehensive, multidisciplinary specialty clinics, including chronic graft vs. host disease, immune deficiency, long term follow-up and bone marrow failure.

During a pediatric stem cell transplant, a patient's diseased or damaged bone marrow is replaced with healthy blood stem cells. Patients first receive chemotherapy and/or radiation to eliminate diseased cells and make space in the bone marrow. The stem cells are then given, make their way to the space in the bone marrow and start producing healthy blood cells.


All children referred for a stem cell transplant at Lurie Children's have a multidisciplinary team to support them before and after transplant. A doctor and advanced practice nurse (APN) function as the primary team, caring for the child throughout the transplant process. The goal of this team approach is to provide consistent, expert care from the point of referral to the completion of the transplant. In addition, all nurses who administer chemotherapy have completed the Association of Pediatric Hematology/Oncology Nurses (APHON) Chemotherapy and Biotherapy Provider Program.


Patients and their families benefit from this tight team approach, which combines highly-specialized education of all stem cell transplant specialists with the clinical experience of advanced practice nurses. Each APN focuses on a unique part of the transplant process, maintaining consistency and reinforcing continuity of care. In addition, a primary social worker and a psychosocial team with child life specialists play integral roles in supporting the emotional, social, educational and developmental needs of the patient and family. 

The status of patients preparing for a stem cell transplant is reviewed in dedicated meetings. Team members discuss diagnosis, transplant and donor options and treatment regimens. They also review any insurance, financial, family or cultural concerns.

Make an Appointment

If you’d like to request an appointment with one of our specialists, call 1.800.543.7362 (1.800.KIDS DOC®). You can also request an appointment online.


Your support is important in helping us continue to make a difference in the lives of patients and families. Lurie Children’s relies on philanthropic funding to enhance its programs, services and research for children. To learn more, please contact the Ann & Robert H. Lurie Children’s Hospital of Chicago Foundation at, call 312.227.7500 or make a gift today.


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​Transitioning to Home Care

Almost Home Kids (AHK), now part of the Lurie Children’s family, cares for children with complicated health needs by providing family training, respite care and short-term transitional care in a home-like setting. AHK is staffed with medical professionals and volunteers to make sure every child and their families are prepared for the return home. The Stem Cell Transplantation Program works closely with Almost Home Kids to make the care transition process as easy as possible.

Learn more about AHK.