Marfan Syndrome Program

Marfan syndrome is a heritable disorder of the connective tissue (the part of the body that holds everything together) that affects many organ systems, including the skeleton, the lungs, the eyes and the heart and blood vessels. The condition can affect both men and women of any race or ethnic​ group. It is estimated that 40,000 people in the United States have Marfan syndrome. Learn more about Marfan syndrome’s symptoms, treatment and long-term outlook​.

The Lurie Children​’s Difference

At the core of our unique approach to cardiac care are our experienced, multidisciplinary teams. Working closely with pediatric radiologists​ for interpretation of magnetic resonance angiogr​ams (MRAs), as well as pediatric orthopaedic surgeons and ophthalmologists​, the team sees about 200 patients each year. These same caregivers treat children diagnosed with Loeys-Dietz syndrome, Ehler's-Danlos syndrome and MASS syndrome.

Special​ists

Pediatric cardiologist Luciana T. Young, MD, in collaboration with pediatric geneticist Barbara K. Burton, MD​, leads the team caring for child​ren with Marfan syndrome.

M​ake a​​n Appointment

Call 1.800.543.7362 (1.800.KID​S DOC) to make an appointment. You can also request an appointment online.

Research

The Marfan Trial was a multi-center clinical trial that compared the effects of beta blocker therapy (atenolol) to those of angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndrome. Dr. Young served as the principal site investigator at Lurie Children’s. 

The study found that losartan is as effective as atenolol in leading to a significant decline in body size-indexed aortic root dimension over time. The study also showed a stronger response in younger age groups, suggesting that beginning therapy early in the disease course may be provide a greater benefit.  

Read the press release to learn more.