Inflammatory Bowel Disease 

The Inflammatory Bowel Disease Program is a multidisciplinary program focusing on the care and research of children diagnosed with Crohn’s disease and ulcerative colitis. The program offers patients and their families comprehensive and individualized treatments for pediatric inflammatory bowel disease (IBD).

The Lurie Children’s Difference

Patients are seen by a multidisciplinary team that includes a pediatric gastroenterologist, pediatric nurse practitioner, registered dietitian and a social worker. The dedicated specialists provide ongoing evaluation and therapy for patients with IBD, including second opinions for complex cases. The team focuses on all aspects of care from improving quality of life to preventing complications of the disease.

The program places an emphasis on research in order to advance patient care and improve parent education. Clinical director Jennifer Strople, MD, is a participant in a multi-center, collaborative research consortium for the study of pediatric IBD. The goals of this research network are to characterize and describe the pediatric IBD population, identify risk factors for development of IBD and evaluate and compare the effectiveness and safety of various treatments of IBD.

Program specialist Jeffrey Brown, MD, participates in laboratory research focused on identifying the specific localization of effector cell trafficking within the colon and what role these pathways play in the establishment of memory function. The long-term objective is to better define pathways of colonic recruitment and establish what factors maintain memory function within the effector compartment of the colon. We hope our research efforts will improve treatment for children with hard-to-treat IBD conditions.

Program specialist, Joshua B. Wechsler, MD, conducts translational laboratory research focused on understanding novel pathways that lead to the development of inflammation associated with Ulcerative Colitis. Specifically, Dr. Wechsler is focused on the role of mast cells, histamine, the histamine 4-receptor and interleukin-6 in the recruitment of innate immune cells, such as neutrophils, to the colon. Neutrophils are a critical aspect of the inflammatory response in ulcerative colitis, thus the overall goal of this research is to facilitate the development of novel treatment options for patients with difficult-to-treat disease.

Our Specialists

Dr. Strople, is Clinical Director of the program. She is supported by members of the IBD program including Dr. Brown and Dr. Wechsler; Beata Borawski, APN; Sally Schwartz, RD; and Amelia Cima, RN. Dr. Strople is board-certified in pediatric gastroenterology and pediatrics. Members of the IBD program participate in both clinical and laboratory research to advance understanding of this complex disease.

Make an Appointment

If you’d like to request an appointment with one of our specialists, call 1.800.543.7362 (1.800.KIDS DOC®). You can also request an appointment online.

Philanthropy

Your support is important in helping us continue to make a difference in the lives of patients and families. Lurie Children’s relies on philanthropic funding to enhance its programs, services and research for children. To learn more, please contact the Ann & Robert H. Lurie Children’s Hospital of Chicago Foundation at foundation@luriechildrens.org, call 312.227.7500 or make a gift today.