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Ulcerative Colitis

Ulcerative Colitis
Ulcerative colitis is an inflammatory bowel disease in which the inner lining of the large intestine (colon or bowel) and rectum become inflamed. Inflammation usually begins in the rectum and lower intestine and spreads upward to the entire colon. Ulcerative colitis rarely affects the small intestine except for the lower section. The inflammation causes diarrhea, or frequent emptying of the colon. As cells on the surface of the lining of the colon die and slough off, ulcers form, causing pus, mucus and bleeding.

The cause of ulcerative colitis is unknown, and currently there is no cure, except through surgical removal of the colon. Although much scientific evidence shows that people with ulcerative colitis have abnormalities of the immune system, physicians do not know whether these abnormalities are a cause or result of the disease. There is little proof that ulcerative colitis is caused by emotional distress or sensitivity to certain foods or food products, or is the result of an unhappy childhood.

Ulcerative colitis requires long-term medical care. There may be periods when the symptoms go away that last for months or even years. However, usually symptoms eventually return. Only in rare cases, when complications occur, is the disease fatal. If only the rectum and lower colon are involved, the risk of cancer is not higher than normal. However, the risk of colon cancer is greater than normal in children with widespread ulcerative colitis.
Symptoms
The most common symptoms for ulcerative colitis include:
  • Abdominal pain
  • Bloody diarrhea:
  • Fatigue:
    Weight loss:
    Loss of appetite:
    Rectal bleeding:
    Loss of body fluids and nutrients:
    Anemia caused by severe bleeding:
    Sometimes children also experience:
    •    Skin lesions
    •    Joint pain
    •    Inflammation of the eyes
    •    Liver disorders
    •    Osteoporosis
    •    Rashes
    •    Anemia
    •    Kidney stones
    The symptoms of ulcerative colitis may resemble other conditions or medical problems. Consult your child's physician for a diagnosis.

    Diagnosis
    A thorough physical examination, including blood tests to determine whether an anemic condition exists, or if the white blood cell count is elevated (a sign of inflammation), is part of the diagnostic process. Symptoms that suggest ulcerative colitis may also be evaluated with the following procedures:
    •    Stool sample - to check for bleeding or infection
    •    Colonoscopy - a test that uses a long, flexible tube with a light and camera lens at the end (colonoscope) to examine inside the large intestine.
    •    Biopsy - removal of a sample of tissue (rom the lining of the colon) to examine under the microscope.
    •    Barium enema - a procedure performed to examine the large intestine for abnormalities. A fluid called barium (a metallic, chemical, chalky, liquid used to coat the inside of organs so that they will show up on an x-ray) is given into the rectum as an enema. An x-ray of the abdomen shows strictures (narrowed areas), obstructions (blockages), and other problems.
    Treatment
    Specific treatment will be determined by your child's physician based on the following:
    •    the child's age, overall health, and medical history
    •    The extent of the disease
    •    The child's tolerance for specific medications, procedures, or therapies
    •    The expectations for the course of the disease
    •    Your opinion or preference

    While there is no special diet for ulcerative colitis, children may be able to control mild symptoms simply by avoiding foods that seem to upset their intestines. When treatment is necessary, it must be tailored for each case, because what may help one patient may not help another.

    Children are also given needed emotional and psychological support. Treatment may include:

    Medication
    Abdominal cramps and diarrhea may be helped by medications that reduce inflammation in the colon. More serious cases may require steroid drugs, antibiotics, or drugs that affect the body's immune system.

    Hospitalization
    Children with ulcerative colitis occasionally have symptoms severe enough to require hospitalization to correct malnutrition and to stop diarrhea and loss of blood, fluids, and mineral salts. The patient may need a special diet, feeding through a vein, medications, or, in some cases, surgery.

    Surgery
    Most children with ulcerative colitis do not need surgery. However, about 20 to 40 percent of ulcerative colitis children eventually require surgery for removal of the colon because of massive bleeding, chronic debilitating illness, perforation of the colon, or risk of cancer.
    Sometimes, removing the colon is suggested when medical treatment fails or the side effects of steroids or other drugs threaten the patient's health. There are several surgical options:

    Proctocolectomy
    The most common surgery is the proctocolectomy (removal of the entire colon and rectum) with ileostomy (creation of a small opening in the abdominal wall where the tip of the lower small intestine, the ileum, is brought to the skin's surface to allow drainage of waste).

    Ileoanal anastomosis
    Sometimes, ileoanal anastomosis (pull-through operation), can be performed. The diseased portion of the colon is removed and the outer muscles of the rectum are preserved. The ileum is attached inside the rectum, forming a pouch, or reservoir, that holds the waste. This allows the patient to pass stool through the anus in a normal manner, although the bowel movements may be more frequent and watery than usual.
    Programs
    The Inflammatory Bowel Disease Program focuses on treating children diagnosed with ulcerative colitis and Crohn’s disease. The multidisciplinary team provides comprehensive care for each patient, from improving quality of life to preventing complications of the disease.
    Make an Appointment
    If you’d like to request an appointment with one of our specialists from the Division of Gastroenterology, Hepatology & Nutrition, call 1.800.543.7362 (1.800.KIDS DOC®). You can also request an appointment online.

    Ulcerative colitis is an inflammatory bowel disease in which the inner lining of the large intestine (colon or bowel) and rectum become inflamed. Inflammation usually begins in the rectum and lower intestine and spreads upward to the entire colon. Ulcerative colitis rarely affects the small intestine except for the lower section. The inflammation causes diarrhea, or frequent emptying of the colon. As cells on the surface of the lining of the colon die and slough off, ulcers form, causing pus, mucus and bleeding.

    The cause of ulcerative colitis is unknown, and currently there is no cure, except through surgical removal of the colon. Although much scientific evidence shows that people with ulcerative colitis have abnormalities of the immune system, physicians do not know whether these abnormalities are a cause or result of the disease. There is little proof that ulcerative colitis is caused by emotional distress or sensitivity to certain foods or food products, or is the result of an unhappy childhood.

    Ulcerative colitis requires long-term medical care. There may be periods when the symptoms go away that last for months or even years. However, usually symptoms eventually return. Only in rare cases, when complications occur, is the disease fatal. If only the rectum and lower colon are involved, the risk of cancer is not higher than normal. However, the risk of colon cancer is greater than normal in children with widespread ulcerative colitis.

    Symptoms

    The most common symptoms for ulcerative colitis include:

    • Abdominal pain
    • Bloody diarrhea
    • Fatigue
    • Weight loss
    • Loss of appetite
    • Rectal bleeding
    • Loss of body fluids and nutrients
    • Anemia caused by severe bleeding

    Sometimes children also experience:

    • Skin lesions
    • Joint pain
    • Inflammation of the eyes
    • Liver disorders
    • Osteoporosis
    • Rashes
    • Anemia
    • Kidney stones

    The symptoms of ulcerative colitis may resemble other conditions or medical problems. Consult your child's physician for a diagnosis.

    Diagnosis

    A thorough physical examination, including blood tests to determine whether an anemic condition exists, or if the white blood cell count is elevated (a sign of inflammation), is part of the diagnostic process. Symptoms that suggest ulcerative colitis may also be evaluated with the following procedures:

    • Stool sample  to check for bleeding or infection
    • Colonoscopy to examine inside the large intestine.
    • Biopsy - to examine a sample of tissue from the lining of the colon
    • Barium enema to examine the large intestine for abnormalities. An x-ray of the abdomen shows narrowed areas, blockages and other problems.

    Treatment

    Specific treatment will be determined by your child's physician based on the following:

    • The child's age, overall health, and medical history
    • The extent of the disease
    • The child's tolerance for specific medications, procedures, or therapies
    • The expectations for the course of the disease
    • Your opinion or preference

    While there is no special diet for ulcerative colitis, children may be able to control mild symptoms simply by avoiding foods that seem to upset their intestines. When treatment is necessary, it must be tailored for each case, because what may help one patient may not help another.

    Children are also given needed emotional and psychological support. Treatment may include:

    Medication
    Abdominal cramps and diarrhea may be helped by medications that reduce inflammation in the colon. More serious cases may require steroid drugs, antibiotics, or drugs that affect the body's immune system.

    Hospitalization
    Children with ulcerative colitis occasionally have symptoms severe enough to require hospitalization to correct malnutrition and to stop diarrhea and loss of blood, fluids, and mineral salts. The patient may need a special diet, feeding through a vein, medications, or, in some cases, surgery.

    Surgery
    Most children with ulcerative colitis do not need surgery. However, about 20 to 40 percent of ulcerative colitis children eventually require surgery for removal of the colon because of massive bleeding, chronic debilitating illness, perforation of the colon, or risk of cancer. Sometimes, removing the colon is suggested when medical treatment fails or the side effects of steroids or other drugs threaten the patient's health. There are several surgical options:

    Proctocolectomy
    The most common surgery is the proctocolectomy (removal of the entire colon and rectum) with ileostomy (creation of a small opening in the abdominal wall where the tip of the lower small intestine, the ileum, is brought to the skin's surface to allow drainage of waste).

    Ileoanal anastomosis
    Sometimes, ileoanal anastomosis (pull-through operation), can be performed. The diseased portion of the colon is removed and the outer muscles of the rectum are preserved. The ileum is attached inside the rectum, forming a pouch, or reservoir, that holds the waste. This allows the patient to pass stool through the anus in a normal manner, although the bowel movements may be more frequent and watery than usual.

    Programs

    The Inflammatory Bowel Disease Program focuses on treating children diagnosed with ulcerative colitis and Crohn’s disease. The multidisciplinary team provides comprehensive care for each patient, from improving quality of life to preventing complications of the disease.

    Make an Appointment

    If you’d like to request an appointment with one of our specialists from the Division of Gastroenterology, Hepatology & Nutrition, call 1.800.543.7362 (1.800.KIDS DOC®). You can also request an appointment online.

     

    Related Specialties & Services

    Read about the specialty areas and services that treat Ulcerative Colitis.